Characterization of Clostridioides difficile Strains from an Outbreak Using MALDI-TOF Mass Spectrometry

A recent study in Microorganisms reports the first case of a C. difficile tcdA⁺/tcdB^–outbreak strain. This C. difficile strain has a functional copy of the Toxin A gene (tcdA) that produces Toxin A but contains a mutation in the Toxin B gene (tcdB), limiting the ability to detect infections by molecular tests that target the tcdB region to detect infection. Click here to view the article.