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T5016 - ASCA-CHEK

The ASCA-CHEK test is an ELISA for the qualitative detection of human anti-S. cerevisiae antibodies (ASCA) in feces. The test result is used as an aid in the diagnosis of Crohn's disease in combination with clinical and laboratory findings.

ASCA-CHEKAn estimated 1 million Americans suffer from inflammatory bowel disease (IBD) which is comprised of Crohn's disease and ulcerative colitis. IBD is characterized by a chronic inflammatory response that results in damage to the intestinal lining. Crohn's disease may involve the entire gastrointestinal tract, whereas ulcerative colitis only affects the large bowel. These two distinct diseases require a rapid differential diagnosis for optimal treatment. The ASCA-CHEK test is an enzyme-linked immunoassay (EIA) for detecting ASCA in human feces. The test provides a method utilizing antigens of Saccharomyces cerevisiae for measuring total fecal ASCA as an aid to distinguish Crohn's disease from other gastrointestinal illnesses such as ulcerative colitis and irritable bowel syndrome.

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